Mechanical Ventilation & Ventricular Assist Devices

Cardiac Remodeling and Recovery: Lessons from Mechanical Ventricular Assist Devices

Cardiac injury, regardless of etiology, typically leads to an increase in wall stress, decreased compliance, reduced systolic function, and progressive chamber dilation. This process is termed “remodeling” and is associated with a worse prognosis in patients with heart failure. Several drugs have been shown to have an effect on inducing reverse remodeling or reducing ventricular dilatation, inc...

Left Ventricular Assist Devices.

Pediatric ventricular assist devices.

The field of pediatric mechanical circulatory support with ventricular assist devices has lagged significantly behind that of adult patients. However, there is increasing attention on the emerging field of pediatric ventricular assist device support. In this review, part of the Pediatric Cardiac Intensive Care Society/Extracorporeal Life Support Organization Joint Consensus Statement on Mechani...

Ventricular assist devices in pediatrics

The implantation of a mechanical circulatory device for end-stage ventricular failure is a possible therapeutic approach in adult and pediatric cardiac surgery and cardiology. The aim of this article is to present mechanical circulatory assist devices used in infants and children with special emphasis on extracorporeal membrane oxygenation, Berlin Heart assist device, centrifugal pump and Medos...

Ventricular assist devices for all?

In the past 5 years, the numbers of ventricular assist device (VAD) systems implanted worldwide have increased exponentially. Thus, since the introduction of the HeartMate II LVAD by Thoratec (Thoratec Inc., Pleasanton, CA, USA) over 10 000 of these pumps have been implanted. The HVAD manufactured by HeartWare (HeartWare Inc., Framingham, MA, USA) has also found widespread application in Europe...